Search Space estimate of Garcia et al. (2024) study

The Southern California Children’s Health Study (CHS) was started in 1992 and continues to this time. Currently, it contains three cohorts recruited across 16 southern Californian communities and included in a follow study in adulthood:

• fourth graders (aged ~9-10 years) in 1992-1993 (cohort “C”)
• fourth graders (aged ~9-10 years) in 1995-1996 (cohort “D”)
• kindergarteners and first graders (aged ~5-7 years) in 2002-2003 (cohort “E”)

Beginning in their respective baseline year and continuing until high school graduation, annual or biannual questionnaires collected a range of information, including demographic characteristics, housing characteristics, prevalence and incidence of bronchitic symptoms, report of doctor-diagnosed asthma, family history of asthma, history of smoking in the household, and residential history.